Feeding skunk kits is a careful art involving 15 cups of fruit and veggies, a dozen eggs, and 15 cups of dog food, and more food in a single day. More information Adding us as a Preferred Source in Google by using this link indicates that you would like to see more of our content in Google News results. Please sir, may I have some more? Breakthroughs, discoveries, and DIY tips sent six days a week. By signing up, you confirm you are 16+, will receive newsletters and promotional content and agree to our Terms of Use and acknowledge the data practices in our Privacy Policy .

Can you eat too much sugar free candy? But it'll probably just send you running to the bathroom. More information Adding us as a Preferred Source in Google by using this link indicates that you would like to see more of our content in Google News results. Sugar-free candy generally replaces sugar with either artificial sweeteners or sugar alcohols. Breakthroughs, discoveries, and DIY tips sent six days a week.

Children under 16 will be banned from buying high-caffeine energy drinks in England from April, the government has said. Drinks containing more than 150mg of caffeine per litre will be illegal to sell to children and younger teenagers in shops, restaurants, cafes, vending machines and online. Lower-caffeine soft drinks, such Diet Coke, are not affected and neither are tea and coffee. However, drinks including Red Bull, Monster, Relentless and Prime would all breach the limit. The new rules aim to reduce obesity levels in children and prevent issues such as disrupted sleep, increased anxiety and lack of concentration, as well as poor school results.

Follow this section to personalize your feed and get instant alerts. Follow Go to your personalized feed WHY FOLLOW? Smart Alerts: Get notified about major news as it happens. Follow this tag to personalize your feed and get instant alerts. Follow Go to your personalized feed WHY FOLLOW?

Follow this section to personalize your feed and get instant alerts. Follow Go to your personalized feed WHY FOLLOW? Smart Alerts: Get notified about major news as it happens. Follow this tag to personalize your feed and get instant alerts. Follow Go to your personalized feed WHY FOLLOW? Smart Alerts: Get notified about major news as it happens.

Plus: The US House has passed new youth online safety legislation. AI agents are not your "coworkers" Imagine coming in to work to learn that a new underling will report to you. The worker is not a person but an AI tool--one that your company nonetheless calls Alex, an "employee" with a title and defined responsibilities. How well do you think you would work with Alex? If you're anything like the managers studied by Boston University professor Emma Wiles, treating that AI as a coworker would lead you to do a worse job. They caught 18% fewer errors when the work was attributed to an agentic AI employee rather than a chatbot. This is an alarming glimpse of the future Silicon Valley is hurling us toward.

Although Large Language Models (LLMs) have demonstrated remarkable progress, their proficiency in graph-related tasks remains notably limited, hindering the development of truly general-purpose models. Previous attempts, including pretraining graph foundation models or employing supervised fine-tuning, often face challenges such as the scarcity of large-scale, universally represented graph data. We introduce G1, a simple yet effective approach demonstrating that Reinforcement Learning (RL) on synthetic graph-theoretic tasks can significantly scale LLMs' graph reasoning abilities. To enable RL training, we curate Erdős, the largest graph reasoning dataset to date, comprising 50 diverse graph-theoretic tasks of varying difficulty levels, 100k training data and 5k test data, all drived from real-world graphs.

Protein-protein interactions (PPIs) are governed by surface complementarity and hydrophobic interactions at protein interfaces. However, designing diverse and physically realistic protein structure and surfaces that precisely complement target receptors remains a significant challenge in computational protein design. In this work, we introduce PepBridge, a novel framework for the joint design of protein surface and structure that seamlessly integrates receptor surface geometry and biochemical properties. Starting with a receptor surface represented as a 3D point cloud, PepBridge generates complete protein structures through a multi-step process. First, it employs denoising diffusion bridge models (DDBMs) to map receptor surfaces to ligand surfaces. Next, a multi-model diffusion model predicts the corresponding structure, while Shape-Frame Matching Networks ensure alignment between surface geometry and backbone architecture. This integrated approach facilitates surface complementarity, conformational stability, and chemical feasibility. Extensive validation across diverse protein design scenarios demonstrates PepBridge's efficacy in generating structurally viable proteins, representing a significant advancement in the joint design of top-down protein structure.

Despite their outstanding performance in numerous applications, large language models (LLMs) remain prone to hallucinations, generating content inconsistent with their pretraining corpora. Currently, almost all contrastive decoding approaches alleviate hallucinations by introducing a model susceptible to hallucinations and appropriately widening the contrastive logits gap between hallucinatory tokens and target tokens. However, although existing contrastive decoding methods mitigate hallucinations, they lack enough confidence in the factual accuracy of the generated content. In this work, we propose Multi-Model Contrastive Decoding (MCD), which integrates a pretrained language model with an evil model and a truthful model for contrastive decoding. Intuitively, a token is assigned a high probability only when deemed potentially hallucinatory by the evil model while being considered factual by the truthful model. This decoding strategy significantly enhances the model's confidence in its generated responses and reduces potential hallucinations. Furthermore, we introduce a dynamic hallucination detection mechanism that facilitates token-by-token identification of hallucinations during generation and a tree-based revision mechanism to diminish hallucinations further. Extensive experimental evaluations demonstrate that our MCD strategy effectively reduces hallucinations in LLMs and outperforms state-of-the-art methods across various benchmarks.

We propose SPARTAALIGNMENT, an algorithm to collectively align multiple LLMs through competition and combat. To complement a single model's lack of diversity in generation and biases in evaluation, multiple LLMs form a "sparta tribe" to compete against each other in fulfilling instructions while serving as judges for the competition of others. For each iteration, one instruction and two models are selected for a duel, the other models evaluate the two responses, and their evaluation scores are aggregated through a adapted elo-ranking based reputation system, where winners/losers of combat gain/lose weight in evaluating others.